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Yes, these were successes, but the successes could have been bigger if we had really paid attention to marketing. He started a covid-19 vaccine company. Steve Kirsch Executive Director at COVID-19 Early Treatment Fund (2020-present) Author has 176 answers and 1.7M answer views Updated 1 y Both. Infoseek lost out to Yahoo; it had a chance to grow bigger, but it didn't. Medium revoked my account for life. We need to keep people out of the hospital in the first place. In October, the group reported that, while a few patients in the placebo group ended up in the hospital, none of the patients receiving fluvoxamine got sick enough to go. To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here. In severe cases, it takes longer. [NIH] doesnt want any of these treatments. The ICER independent review showed fluvoxamine is more effective than Molnupiravir: Read this article I wrote about using fluvoxamine correctly for COVID. Its all about NIH saying it is OK. . Thanks for working tirelessly to help others. How I recommend people treat COVID and the fascinating backstory of how fluvoxamine was discovered. It is very safe: There is no evidence fluvoxamine is harmful and led to a worse outcome. Unfortunately, as Jeffrey Morris at UPenn points out, public health officials and scientists have done plenty to undermine their own authority, like claiming masks dont work, downplaying the natural immunity conveyed by previous covid infections, and not doing enough public communication about vaccine safety surveillance systems. He was recently featured on 60 Minutes, . The paramedics will think you are on drugs. In other cases, stop cold turkey. 1991-1992 to 7.1% in 2001-2002. It is about following orders and making money for the drug companies and protecting the doctor from liability and losing his medical license. How can we get fluvoxamine? They were giving covid patients the antidepressant fluvoxamine as soon as possible after diagnosis, based on anecdotes about the drug limiting the runaway immune response that causes many severe symptoms. People are dying. Ivermectin has a very high quality systematic review, the highest possible level in Evidence Based Medicine. Always be self aware when using fluvoxamine. I think we did rigorous reviews of proposals for research.. Some speaker, off camera, went on a . See this Wall Street Journal op-ed. Your best bet is to. Although the average effect size is 100% with a p-value of <.0001, The Fisher exact test on the combined data suggests that there is a 95% chance that the effect size is at least a 75% reduction in hospitalization rate. People are dying because of physician fear of a new treatment with a 100% success rate and a solid mechanism of action. . That was a lie. Its sad, but its true, he told me. Other SSRIs work as well, but fluvoxamine activates the Sigma-1 receptor the most of the SSRIs which is why it was chosen. Fluoxetine is just as effective. Fluvoxamine is used commonly to treat obsessive-compulsive disorder (OCD), social anxiety disorder and depression. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. This advice is now outdated. fluvoxamine The fast, easy, safe, simple, low cost treatment for COVID that has worked 100% of the time to prevent hospitalization that nobody wants to talk about We now have a viable solution to reduce COVID hospitalization and mortality; Read More fluvoxamine Got COVID? I agreed to do it partially because I respect Bob [Siliciano] so much, and partially because I thought the concept was excellent, said former board member Doug Richman, a prominent HIV drug researcher at the University of California San Diego and former member of the funds scientific advisory board. But how many did it help? Last Checked: 03/02/2023. It was tested in coronavirus patients because fluvoxamine has very strong anti-inflammatory properties. Steve Kirsch said scientists and clinicians are studying a host of drugs and therapeutics to create a new line of defence against the virus but clinical trials are yet to lead to conclusive. The medical community doesnt care about saving lives. They knew in advance it was coming and on the day the paper was published they ignored it entirely. So much for evidence-based medicine. If you ask your doctor for any evidence that fluvoxamine doesnt work or is harmful (like a DB-RCT which is the only thing they trust), they will show you nothing. Author Affiliations Article Information. Less than a week later, David Seftel read about the Lenze trial, and ignored the JAMA advice. The collateral damage is that, now, a lot of people dont trust scientific leaders or the scientific community. He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. The WashU Phase 3 study hasnt been disclosed yet, but they had compliance problems with their patients this time around (phase 2 was local so the patients got the drug early and also were very compliant and the placebo group was truly taking nothing). Reached by email, the two fluvoxamine investigators denied that there was any effort to suppress their research, and they were cautiously optimistic about their continued study. Nobody in the medical community is speaking out about how hypocritical the medical community is for ignoring the positive Phase 3 trial results and instead following whatever the NIH or FDA says. There were no studies reported out so far where fluvoxamine made things worse or neutral. If you ask your doctor for any evidence that fluvoxamine doesnt work or is harmful (like a DB-RCT which is the only thing they trust), they will show you nothing. If you continue to get this message, The. A very short op-ed arguing for using fluvoxamine against COVID. Perhaps Kirschs most effective tactic, though, is simply his willingness to outlast everyone else. Decreasing the dosage or stopping the medication will mitigate symptoms within hours. Everyone is stunned, but nobody is surprised. You can use fluoxetine as well (aka Prozac). Dose escalation studies in lupus patients and in rheumatoid arthritis patients established that 800 mg per day for life and 1,200 mg per day for 6 weeks are extremely well-tolerated. All the researchers are convinced the drug works. Kirsch, despite having direct access to the actual trial runner, eventually became convinced a correct interpretation of the data would show that hydroxychloroquine worked. Di scl ai mer: T he vi ews expressed i n t hi s art i cl e are my own personal opi ni on based on my 1, 000+ hour st udy of cut t i ng edge . Compulsive fiddling with your mask? At that dose, no side effects were reported for his patients (I know of only one person who had mild nausea at that dose) and everyone reversed out their symptoms in an average of 3 days. He thinks # killed by vax could be anywhere between 0 and 150K people dead.. Fluvoxamine for COVID-19 summary Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008 Google Docs This is a more comprehensive look at the key evidence supporting fluvoxamine: Fluvoxamine for COVID-19 To date, we have heard nothing suggesting the drug doesn't work or could be harmful. skirsch.io. Steve Kirsch is baffled. My website www.skirsch.io has tons of info on fluvoxamine with all the links. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. Ms Tech | Pexels (hands); Kirsch (skirsch.com), Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting, supports Technology Review's reporting on covid, anti-covid-vaccine, pro-ivermectin pundit, Roomba testers feel misled after intimate images ended up on Facebook, How Rust went from a side project to the worlds most-loved programming language. All the medical journals refused to publish the meeting notes (rejected by 6 journals). I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. Here is the latest version. Here are the key things you should know about fluvoxamine for COVID: It works. Its really, really common for a small effect, something that looks exciting, to be a statistical fluke when you look at a larger population. Kirsch and his group received a fresh wave of attention off hopeful trials of the antidepressant fluvoxamine, which ultimately won him a spot on 60 Minutes in March. It is currently approved for treatment of depression and obsessive compulsive disorder (OCD). I will . The premise made sense: Most experts were predicting vaccines would take years, while finding helpful drugs with known safety profiles could shortcut the approval process. @stkirsch. He has a history of giving away some of his millions to good causes, and when COVID-19 began. Boulwares trial was part of a wider movement to bulk up the evidence base underlying standard covid treatments, and one of several trials that found no benefit to using hydroxychloroquine. From the French observational data (see the very last page), it appears that the biggest effect is limiting serotonin release (any SSRI will do that). Online Status. So check the side-effects list to be familiar with which side-effects are associated with which drug so if you have a side-effect, youll know which drug to reduce or eliminate. He started a new pseudonymous account, @VaccineTruth2, to continue broadcasting messages. He is very smart, and he knows that he is very smart, and hesometimes he behaves like he thinks hes the smartest guy in the room, whether he is or isnt, he told me. We have a bounty of vaccines and more on the way, but drugs that treat the disease are vital too if we want to keep people alive and bring the pandemic under control. Hes refused to accept the results of a hydroxychloroquine trial that showed the drug had no value in treating covid, for instance, instead blaming investigators for poor study design and statistical errors. One of the first CETF grants was to investigate the antimalarial hydroxychloroquine. The rest of the board soon followed. For example, tylenol+caffeine+fluvoxamine can lead to serotonin syndrome. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. Another CETF grant, though, yielded far more exciting results. See more below. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. In the early days of the pandemic, as billions of dollars poured into the hunt for novel treatments and vaccines, veteran Silicon Valley entrepreneur Steve Kirsch did what hes always done: He went looking for an underdog. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. On January 22, 2021, thirty key opinion leaders (KOL) from NIH, CDC, and leading academic institutions met to review the evidence for using fluvoxamine for treating COVID. The anecdotal data of 100% success rates is further icing on the cake. They never make things worse so are safe to try. Who knows, Morris replied. There is an executive summary below, but the most important thing is that top infectious disease docs who have looked at all the evidence (including the two clinical trial results) believe the effect size is 75% or more in reducing the hospitalization rate. The agency quickly slapped down the comments from Kirsch, a tech mogul with a fortune once estimated at $230 million, even as the claims triggered a flurry of false social-media posts attributing. I am not aware of a single case where taking the made things worse, e.g., person was doing fine BEFORE the drug and symptoms worsened after taking the drug. Indeed, some of the most prominent people spreading misinformation about ivermectin and vaccines today began by promoting hydroxychloroquineincluding by claiming to debunk Boulwares data analysis. The sooner you start, the better the outcomes. Online. The FDA is will take months to deliberate on the fluvoxamine EUA application that we submitted on January 29. Our in-depth reporting reveals whats going on now to prepare you for whats coming next. The web value rate of skirsch.io is 2 . Both drugs have compelling data that is hard to explain if the drug doesn't work. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. In September, he resigned as CEO and gave up his board seat. I also think it makes a lot of sense to look for pre-existing drugs that can help treat covid symptoms. You see this with people who have a lot of money, who think that reflects their intelligence, Richman told me. Steve Kirsch is a Silicon Valley philanthropist. Fluvoxamine is way better than Molnupiravir, but the NIH doesnt approve drugs on effectiveness. If you start later, doctors use higher dosages and compliance becomes a bigger problem. Pretty much nothing changed when the Phase 3 trial confirmed fluvoxamine worked. Discover special offers, top stories, Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. Do they sell it anywhere? During our first conversation, which turned into a multi-hour Zoom session, Kirsch paced through the rooms of his cavernous house with his phone held at chest level, rarely looking down at the camera. Compulsive hand washing? Article about the rejection (Stat News) Article about the fluvoxamine rejection (The Verge) NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). Soon after his appearance on the DarkHorse podcast, several partners of his most recent startup, M10, expressed concerns about the increasing extremism of Kirschs vaccine views. He considers himself an expert in something that he doesnt have training or experience in, and hes not following scientific methods to assess data.. Adverse reactions/side effects. Seftel used a 50mg BID dosing for 14 days which was one third of the max dose used in the Lenze study. Still, in the moment, his question threw me, and I stuttered. The NIH wrote a bullshit rejection because the FDA told them not to approve it. Almost 2.5 million people signed up to Dr. B with the promise of getting leftover vaccines. Steve Kirsch is looking for an explanation for 171,000 excess deaths. Sadly, doctors and public health officials refuse to instruct patients to seek early treatment. But an Editor's Note urged physicians to treat this as a hypothesis and not as a basis for clinical decision-making. In that same IEEE Spectrum story about his then-new startup, Propel Software, he said he felt successful, but not famous. Dosage there is 30mg once a day. If not, they should at least acknowledge that fluvoxamine might be helpful by at least listing it as a possibility. In May, all 12 members of CETFs scientific advisory board resigned, citing his alarming dangerous claims and erratic behavior. Author Affiliations . But the potential upsides. By the beginning of September, he was no longer the companys CEO, replaced by his co-founder, Marten Nelson. [https://www.quora.com/What-is-the-current-treatment-for-Covid-19/answer/, The most urgent need in the country right now is to reduce. . Hes also recently increased the number of Americans he claim have been killed by the vaccine from 25,0000, to 150,000, or even as many as 250,000 Americans. Read More fluvoxamine The Fluvoxamine FAQ These people never called the researchers whose trials they claimed showed no effect. Get your prescription in advance of getting COVID. Medicine isnt about saving lives anymore. The NIH never did a risk benefit analysis of this drug. . It does not matter how many lives will be saved. What's even worse is that a third of recovered patients from COVID will return to the hospital within 5 months and 1 in 8 die. It was so bad you couldnt even see the babys body through all the blood, Kirsch said. While Fauci was crafting national pandemic policies, Fauci's wife [Christine Grady, Chief Bioethicist, NIH] was back stopping [them]." Report coming soon. Its all about NIH saying it is OK. Medicine today is driven by government opinion, not science. We pretty much practice government agency opinion medicine all over the world now, with just a few exceptions. The claim that the spike is toxic, that came directly from the [DarkHorse episode]. But fear of trying something new prevents any doctor from giving this drug a try. I see it all the time on social media, Morris told me. Even though an expert panel was overwhelmingly convinced in just one hour, hearing a very small subset of all the supporting evidence, the organizations that they belong to are taking their time. If you start later, doctors use higher dosages and compliance becomes a bigger problem. When the pandemic started, he created the COVID-19 Early Treatment Fund (CETF) to fund researchers working on repurposed drugs including fluvoxamine which reduces death from COVID by a factor of 12. People who report not tolerating the drug are typically prescribed too high a dose. Hes also made several videos and podcasts with Vladimir Zelenko, the conspiracy theorist doctor who convinced Trump to take hydroxychloroquine. . Los Altos Hills resident Steve Kirsch funded research into the drug fluvoxamine as a treatment for COVID-19. Doctors are afraid that even with a 37-year safety record of this drug, that something will go terribly wrong and they will be blamed. I've collected fluvoxamine evidence here for convenient access. Medium banned him for misinformation. ALWAYS check with your doctor and report any medications you are taking before or plan to take after you start taking fluvoxamine. Three of the four outpatient trials have been reported out: all were successful. He's discovered a common medication that's highly effective in minimizing the impacts of COVID-19 - two studies have proven so. See the repository above. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 7.76K 31 'This Has Cost Millions Of Lives': Steve Kirsch On Suppression Of Repurposed Drugs And A Spike In Deaths 5 Months After Vaccine Rollout By Jan Jekielek American Thought Leaders / The Epoch Times November 24, 2022 Show more Why the FDA should grant an EUA for fluvoxamine immediately, a brilliant op-ed in the Wall Street Journal, "Too much caution is killing COVID patients. Mar. . Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. Steve calls himself a "medical philanthropist" who says "the most important thing to me is saving lives." In . In short, a lot of mumbo jumbo.